BL02U1

Kai Jiang, Xu Chen, Xiaoli Yan, Guangjun Li, Zhi Lin, Zixin Deng, Shukun Luo, Xudong Qu An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin. Proceedings of the National Academy of Sciences, 121(11), e2321722121. (2024).

Longying Jiang, Xueke Liu, Xujun Liang, Shuyan Dai, Hudie Wei, Ming Guo, Zhuchu Chen, Desheng Xiao, Yongheng Chen Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32(4), 467-475.e463. (2024).

Wenhua Jiang, Qiangqiang Hou, Hongrui Xu, Kexin Yang, Xiaohui Wang, Kuojun Zhang, Yi Zeng, Wenqiang Li, Bingrui Wang, Guangmei Luo, Xiaofan Zhao, Hui Shen, Yong Xu, Xiaoxing Wu Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. Journal of Medicinal Chemistry, 67(2), 1513-1532. (2024).

Yuping Jin, Jiyuan Ke, Peiyi Zheng, Haiyan Zhang, Zhongliang Zhu, Liwen Niu Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 32(8), 1197-1207.e1194. (2024).

Chunyan Li, Xiaochen Xu, Zhi Geng, Luqian Zheng, Qianqian Song, Xin Shen, Jingjing Wu, Jin zhao, Hongcheng Li, Mengqi He, Xiaoqing Tai, Long Zhang, Jinbiao Ma, Yuhui Dong, Aiming Ren Structure-based characterization and compound identification of the wild-type THF class-II riboswitch. Nucleic Acids Research, 52(14), 8454-8465. (2024).

Dong Li, Yu Xiao, Iana Fedorova, Weijia Xiong, Yu Wang, Xi Liu, Erin Huiting, Jie Ren, Zirui Gao, Xingyu Zhao, Xueli Cao, Yi Zhang, Joseph Bondy-Denomy, Yue Feng Single phage proteins sequester signals from TIR and cGAS-like enzymes. Nature, 635(8039), 719-727. (2024).

Fang-Ru Li, Qingling Wang, Xingming Pan, Hui-Min Xu, Liao-Bin Dong Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angewandte Chemie International Edition, 63(27), e202401669. (2024).

Juan Li, Hong Cui, Yujie Yao, Junling Niu, Jing Zhang, Xu Zheng, Mengmeng Cui, Jia Liu, Tong Cheng, Yuhui Gao, Qiuhong Guo, Shi Yu, Lanfeng Wang, Zhong Huang, Jing Huang, Ke Zhang, Chengyuan Wang, Guangxun Meng Anti-influenza activity of CPAVM1 protease secreted by Bacillus subtilis LjM2. Antiviral Research, 228, 105919. (2024).