BL02U1

Chenming Gu, Jiayuan Liu, Fei Qian, Wenchao Yu, Doudou Huang, Jingshan Shen, Chenguo Feng, Kaixian Chen, Yiming Li, Xiangrui Jiang, Yechun Xu, Liuqiang Zhang Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model. Journal of Medicinal Chemistry, 67(6), 4855-4869. (2024).

Decoding the molecular mechanism of selective autophagy of glycogen mediated by autophagy receptor STBD1. e2402817121 pp.

Yanyun Guan, Jingjie Chen, Hongxin Guan, Tao-Tao Chen, Yan Teng, Zuyun Wei, Zekai Li, Songying Ouyang, Xinhua Chen Structural and Functional Characterization of a Fish Type I Subgroup d IFN Reveals Its Binding to Receptors. The Journal of Immunology, 212(7), 1207-1220. (2024).

Baodian Guo, Qinli Hu, Bangwei Wang, Deqiang Yao, Haonan Wang, Guanghui Kong, Chenyang Han, Suomeng Dong, Fengquan Liu, Weiman Xing, Yuanchao Wang Oomycete Nudix effectors display WY-Nudix conformation and mRNA decapping activity. Journal of Integrative Plant Biology, 66(8), 1548-1552. (2024).

Yunhang Guo, Hai Xue, Nan Hu, Ye Liu, Hanzi Sun, Desheng Yu, Ling Qin, Gongyin Shi, Fan Wang, Lei Xin, Weihua Sun, Fan Zhang, Xiaomin Song, Shuran Li, Qiang Wei, Ying Guo, Yong Li, Xiaoxin Liu, Shuaishuai Chen, Taichang Zhang, Yue Wu, Dan Su, Yutong Zhu, Aiying Xu, Haipeng Xu, Shasha Yang, Zhijun Zheng, Junhua Liu, Xuefei Yang, Xi Yuan, Yuan Hong, Xuebing Sun, Yin Guo, Changyou Zhou, Xuesong Liu, Lai Wang, Zhiwei Wang Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2. Journal of Medicinal Chemistry, 67(10), 7836-7858. (2024).

Yu Han, Yuelin Luo, Bao-Di Ma, Jie Li, Jian-He Xu, Xu-Dong Kong Structural Insights of a cis-Epoxysuccinate Hydrolase Facilitate the Development of Robust Biocatalysts for the Production of l-(+)-Tartrate. Biochemistry, 63(12), 1578-1587. (2024).

Jun-Bin He, Yichen Ren, Peifeng Li, Yi-Pei Liu, Hai-Xue Pan, Lin-Juan Huang, Jiayuan Wang, Pengfei Fang, Gong-Li Tang Crystal Structure and Mutagenesis of an XYP Subfamily Cyclodipeptide Synthase Reveal Key Determinants of Enzyme Activity and Substrate Specificity. Biochemistry, 63(22), 2969-2976. (2024).

Chengtao Hu, Ziyue Chen, Guanchao Wang, Hui Yang, Jianping Ding Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role. Structure, 32(8), 1208-1221.e1204. (2024).