BL02U1

Lulu Hu, Ze Li, Jingdong Cheng, Qinhui Rao, Wei Gong, Mengjie Liu, Yujiang Geno Shi, Jiayu Zhu, Ping Wang, Yanhui Xu Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation. Cell, 155(7), 1545-1555. (2013).

Qing-Hua Hu, Ru-Juan Liu, Zhi-Peng Fang, Jiong Zhang, Ying-Ying Ding, Min Tan, Meng Wang, Wei Pan, Hu-Chen Zhou, En-Duo Wang Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase. Scientific Reports, 3(1), 2475. (2013).

Zehan Hu, Chuangye Yan, Peiyuan Liu, Zhiwei Huang, Rui Ma, Chenlu Zhang, Ruiyong Wang, Yueteng Zhang, Fabio Martinon, Di Miao, Haiteng Deng, Jiawei Wang, Junbiao Chang, Jijie Chai Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism. Science, 341(6142), 172-175. (2013).

Wei Huang, Zhen Gong, Jian Li, Jianping Ding Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism. Journal of Structural Biology, 181(3), 291-299. (2013).

Daohua Jiang, Yan Zhao, Xianping Wang, Junping Fan, Jie Heng, Xuehui Liu, Wei Feng, Xusheng Kang, Bo Huang, Jianfeng Liu, Xuejun Cai Zhang Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A. Proceedings of the National Academy of Sciences, 110(36), 14664-14669. (2013).

Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jintang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, Hening Lin SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature, 496(7443), 110-113. (2013).

Lianying Jiao, Songying Ouyang, Mifang Liang, Fengfeng Niu, Neil Shaw, Wei Wu, Wei Ding, Cong Jin, Yao Peng, Yanping Zhu, Fushun Zhang, Tao Wang, Chuan Li, Xiaobing Zuo, Chi-Hao Luan, Dexin Li, Zhi-Jie Liu Structure of Severe Fever with Thrombocytopenia Syndrome Virus Nucleocapsid Protein in Complex with Suramin Reveals Therapeutic Potential. Journal of Virology, 87(12), 6829-6839. (2013).

Lihua Jin, Xuhui Feng, Hui Rong, Zhifu Pan, Yuka Inaba, Lin Qiu, Weili Zheng, Shengchen Lin, Rui Wang, Zhao Wang, Shanshan Wang, Hongyan Liu, Song Li, Wen Xie, Yong Li The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism. Nature Communications, 4(1), 1937. (2013).