BL19U1

Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng, Meiqin Liu, Yao Zhao, Bing Zhang, Xiaofeng Li, Leike Zhang, Chao Peng, Yinkai Duan, Jing Yu, Lin Wang, Kailin Yang, Fengjiang Liu, Rendi Jiang, Xinglou Yang, Tian You, Xiaoce Liu, Xiuna Yang, Fang Bai, Hong Liu, Xiang Liu, Luke W. Guddat, Wenqing Xu, Gengfu Xiao, Chengfeng Qin, Zhengli Shi, Hualiang Jiang, Zihe Rao & Haitao Yang,Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors. Nature 582, 289–293 (2020).

Masao Ohashi, Cooper Jamieson, Yujuan Cai, Dan Tan, Daiki Kanayama, Man Tang, Sarah Anthony, Jason Chari, Joyann Barber, Elias Picazo, Thomas Kakule, Shugeng Cao, Neil Garg, Jiahai Zhou, K. Houk, Yi Tang, An enzymatic Alder-ene reaction. Nature, 586,64-69 (2020).

Lin Wang, Juehui Wu, Jun Li, Hua Yang, Tianqi Tang, Haijiao Liang, Mianyong Zuo, Jie Wang, Haipeng Liu, Feng Liu, Jianxia Chen, Zhonghua Liu, Yang Wang, Cheng Peng, Xiangyang Wu, Ruijuan Zheng, Xiaochen Huang, Yajun Ran, Zihe Rao, Baoxue Ge, Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature, 577, 682-688(2020).

Wenhao Dai, Bing Zhang, Xia Jiang, Haixia Su, Jian Li, Yao Zhao, Xiong Xie, Zhenming Jin, Jingjing Peng, Fengjiang Liu, Chunpu Li, You Li, Fang Bai, Haofeng Wang, Xi Cheng, Xiaobo Cen, Shulei Hu, Xiuna Yang, Jiang Wang, Xiang Liu, Gengfu Xiao, Hualiang Jiang, Zihe Rao, Lei Zhang, Yechun Xu, Haitao Yang, Hong Liu, Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science, 368,1331-1335 (2020).

Lu Zhang, Yao Zhao, Yan Gao, Lijie Wu, Ruogu Gao, Qi Zhang, Yinan Wang, Chengyao Wu, Fangyu Wu, Sudagar Gurcha, Natacha Veerapen, Sarah Batt, Wei Zhao, Ling Qin, Xiuna Yang, Manfu Wang, Yan Zhu, Bing Zhang, Lijun Bi, Xianen Zhang, Haitao Yang, Luke Guddat, Wenqing Xu, Quan Wang, Jun Li, Gurdyal Besra, Zihe Rao, Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 1211-1219(2020).

Emily Chin, Chenguang Yu, Vincent Vartabedian, Ying Jia, Manoj Kumar, Ana Gamo, William Vernier, Sabrina Ali, Mildred Kissai, Daniel Lazar, Nhan Nguyen, Laura Pereira, Brent Benish, Ashley Woods, Sean Joseph, Alan Chu, Kristen Johnson, Philipp Sander, Francisco Martínez-Peña, Eric Hampton, Travis Young, Dennis Wolan, Arnab Chatterjee, Peter Schultz, Petrassi Michael, John Teijaro, Luke Lairson, Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science, 369, 993-999(2020).

Jin Dou, Maxx Arguilla, Yi Luo, Jian Li, Weizhe Zhang, Lei Sun, Jenna Mancuso, Luming Yang, Tianyang Chen, Lucas Parent, Grigorii Skorupskii, Nicole Libretto, Chenyue Sun, Min Yang, Phat Dip, Edward Brignole, Jeffrey Miller, Jing Kong, Christopher Hendon, Junliang Sun, Mircea Dincă, Atomically precise single-crystal structures of electrically conducting 2D metal–organic frameworks. Nature Materials, 20,222–228 (2021).

Lianpan Dai, Tianyi Zheng, Kun Xu, Yuxuan Han, Lili Xu, Enqi Huang, Yaling An, Yingjie Cheng, Shihua Li, Mei Liu, Mi Yang, Yan Li, Huijun Cheng, Yuan Yuan, Wei Zhang, Changwen Ke, Gary Wong, Jianxun Qi, Chuan Qin, Jinghua Yan, George Gao, A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell, 182, 722-733(2020).