BL02U1

Wei Zhang, Zijian Zhang, Yun Xiang, Dong-Dong Gu, Jinna Chen, Yifan Chen, Shixian Zhai, Yong Liu, Tao Jiang, Chong Liu, Bin He, Min Yan, Zifeng Wang, Jie Xu, Yu-Lu Cao, Bing Deng, Deshun Zeng, Jie Lei, Junxiao Zhuo, Xinxing Lei, Zijie Long, Bilian Jin, Tongsheng Chen, Dong Li, Yidong Shen, Junjie Hu, Song Gao, Quentin Liu Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis. Nature Structural & Molecular Biology, 31(2), 219-231. (2024).

Yaning Zhang, Yanchao Ding, Ziyan Zeng, Rui Zhu, Peiyuan Zheng, Shilong Fan, Qingjuan Cao, Hang Chen, Weishuai Ren, Mengling Wu, Luyao Wang, Juanjuan Du Intra-channel bi-epitopic crosslinking unleashes ultrapotent antibodies targeting NaV1.7 for pain alleviation. Cell Reports Medicine, 5(11), 101800. (2024).

Ying Zhang, Fang Wu, Yongyue Han, Yuzhe Wu, Liqiu Huang, Yuanwei Huang, Di Yan, Xiwen Jiang, Jingyun Ma, Wei Xu Unraveling the assembly mechanism of SADS-CoV virus nucleocapsid protein: insights from RNA binding, dimerization, and epitope diversity profiling. Journal of Virology, 98(8), e00926-00924. (2024).

Qiaoqiao Zhao, Jinlin Bao, Huailong Li, Wei Hu, Yanqiong Kong, Yifeng Zhong, Qiang Fu, Guolyu Xu, Fenmei Liu, Xi Jiao, Jian Jin, Zhenhua Ming Structural and biochemical basis of FLS2-mediated signal activation and transduction in rice. Plant Communications, 5(3), 100785. (2024).

Zhennan Zhao, Xin Li, Yan Chai, Zhifeng Liu, Qihui Wang, George F. Gao Molecular basis for receptor recognition and broad host tropism for merbecovirus MjHKU4r-CoV-1. EMBO reports, 25(7), 3116-3136-3136. (2024).

Xuan Zheng, Zhiwen Chen, Ming Guo, Hong Liang, Xiaojuan Song, Yiling Liu, Zhenling Liao, Yan Zhang, Jing Guo, Yang Zhou, Zhi-min Zhang, Zhengchao Tu, Ye Zhang, Yongheng Chen, Zhang Zhang, Xiaoyun Lu Structure-Based Optimization of Pyrazinamide-Containing Macrocyclic Derivatives as Fms-like Tyrosine Kinase 3 (FLT3) Inhibitors to Overcome Clinical Mutations. ACS Pharmacology & Translational Science, 7(5), 1485-1506. (2024).

Haiyang Zhong, Xinyue Wang, Shicheng Chen, Zhe Wang, Huating Wang, Lei Xu, Tingjun Hou, Xiaojun Yao, Dan Li, Peichen Pan Discovery of Novel Inhibitors of BRD4 for Treating Prostate Cancer: A Comprehensive Case Study for Considering Water Networks in Virtual Screening and Drug Design. Journal of Medicinal Chemistry, 67(1), 138-151. (2024).

Jintong Zhou, Mingyu Xia, Zhenghui Huang, Hang Qiao, Guang Yang, Yunan Qian, Peifeng Li, Zhaolun Zhang, Xinai Gao, Lubin Jiang, Jing Wang, Wei Li, Pengfei Fang Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Communications Biology, 7(1), 742. (2024).