发表文章
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Zenon Konteatis, Jeremy Travins, Stefan Gross, Katya Marjon, Amelia Barnett, Everton Mandley, Brandon Nicolay, Raj Nagaraja, Yue Chen, Yabo Sun, Zhixiao Liu, Jie Yu, Zhixiong Ye, Fan Jiang, Wentao Wei, Cheng Fang, Yi Gao, Peter Kalev, Marc L. Hyer, Byron DeLaBarre, Lei Jin, Anil K. Padyana, Lenny Dang, Joshua Murtie, Scott A. Biller, Zhihua Sui, Kevin M. Marks, Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion. Journal of Medicinal Chemistry, 64, 4430-4449(2021).https://doi.org/10.1021/acs.jmedchem.0c01895
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Sebastiaan Lamers, Qiaoli Feng, Yili Cheng, Sihong Yu, Bo Sun, Maxwell Lukman, Jie Jiang, David Ruiz-Carrillo, Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase. Biological Chemistry, 402, 759-768(2021).https://doi.org/10.1515/hsz-2020-0298
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Robert P. Law, Joao Nunes, Chun-wa Chung, Marcus Bantscheff, Karol Buda, Han Dai, John P. Evans, Adam Flinders, Diana Klimaszewska, Antonia J. Lewis, Marcel Muelbaier, Paul Scott-Stevens, Peter Stacey, Christopher J. Tame, Gillian F. Watt, Nico Zinn, Markus A. Queisser, John D. Harling, Andrew B. Benowitz, Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs. Angewandte Chemie-International Edition, 60, 23327-23334(2021).https://doi.org/10.1002/anie.202109237
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Esther C. Y. Lee, Andrew J. McRiner, Katy E. Georgiadis, Julie Liu, Zooey Wang, Andrew D. Ferguson, Benjamin Levin, Moritz von Rechenberg, Christopher D. Hupp, Michael I. Monteiro, Anthony D. Keefe, Allison Olszewski, Charles J. Eyermann, Paolo Centrella, Yanbin Liu, Shilpi Arora, John W. Cuozzo, Ying Zhang, Matthew A. Clark, Christelle Huguet, Anna Kohlmann, Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. Journal of Medicinal Chemistry, 64, 6730-6744(2021).https://doi.org/10.1021/acs.jmedchem.0c02271
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Huan Lian, Kun Jiang, Ming Tong, Zhe Chen, Xiaoyu Liu, Jorge E. Galan, Xiang Gao, The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response. Nature Microbiology, 6, 658-+(2021).https://doi.org/10.1038/s41564-021-00866-3
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Mingfu Liang, Gaowei Jin, Xingqiao Xie, Wenchao Zhang, Kaiyue Li, Fengfeng Niu, Cong Yu, Zhiyi Wei, Oligomerized liprin-α promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins. Cell Reports, 34, (2021).https://doi.org/10.1016/j.celrep.2021.108901
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Pan Liao, Shiu-Cheung Lung, Wai Lung Chan, Menglong Hu, Geoffrey Kwai-Wai Kong, Thomas J. Bach, Quan Hao, Clive Lo, Mee-Len Chye, Overexpression and Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA Synthase Affect Central Metabolic Pathways in Tobacco. Plant and Cell Physiology, 62, 205-218(2021).https://doi.org/10.1093/pcp/pcaa154
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Ke-Yu Lu, Ben-Ge Xin, Teng Zhang, Na-Nv Liu, Dan Li, Stephane Rety, Xu-Guang Xi, Structural study of the function of Candida Albicans Pif1. Biochemical and Biophysical Research Communications, 567, 190-194(2021).https://doi.org/10.1016/j.bbrc.2021.06.050