BL02U1

Zhenming Jin, Yao Zhao, Yuan Sun, Bing Zhang, Haofeng Wang, Yan Wu, Yan Zhu, Chen Zhu, Tianyu Hu, Xiaoyu Du, Yinkai Duan, Jing Yu, Xiaobao Yang, Xiuna Yang, Kailin Yang, Xiang Liu, Luke W. Guddat, Gengfu Xiao, Leike Zhang, Haitao Yang, Zihe Rao Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nature Structural & Molecular Biology, 27(6), 529-532. (2020).

Bin Ju, Qi Zhang, Jiwan Ge, Ruoke Wang, Jing Sun, Xiangyang Ge, Jiazhen Yu, Sisi Shan, Bing Zhou, Shuo Song, Xian Tang, Jinfang Yu, Jun Lan, Jing Yuan, Haiyan Wang, Juanjuan Zhao, Shuye Zhang, Youchun Wang, Xuanling Shi, Lei Liu, Jincun Zhao, Xinquan Wang, Zheng Zhang, Linqi Zhang Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584(7819), 115-119. (2020).

Dapeng Ju, Wei Zhang, Jiawei Yan, Haijiao Zhao, Wei Li, Jiawen Wang, Meimei Liao, Zhancong Xu, Zhiqiang Wang, Guanshen Zhou, Long Mei, Nannan Hou, Shuhua Ying, Tao Cai, She Chen, Xiaowen Xie, Luhua Lai, Chao Tang, Noheon Park, Joseph S. Takahashi, Niu Huang, Xiangbing Qi, Eric Erquan Zhang Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals. Science Translational Medicine, 12(542), eaba0769. (2020).

Zenon Konteatis, Erin Artin, Brandon Nicolay, Kimberly Straley, Anil K. Padyana, Lei Jin, Yue Chen, Rohini Narayaraswamy, Shuilong Tong, Feng Wang, Ding Zhou, Dawei Cui, Zhenwei Cai, Zhiyong Luo, Cheng Fang, Huachun Tang, Xiaobing Lv, Raj Nagaraja, Hua Yang, Shin-San M. Su, Zhihua Sui, Lenny Dang, Katharine Yen, Janeta Popovici-Muller, Paolo Codega, Carl Campos, Ingo K. Mellinghoff, Scott A. Biller Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma. ACS Medicinal Chemistry Letters, 11(2), 101-107. (2020).

Jun Lan, Jiwan Ge, Jinfang Yu, Sisi Shan, Huan Zhou, Shilong Fan, Qi Zhang, Xuanling Shi, Qisheng Wang, Linqi Zhang, Xinquan Wang Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature, 581(7807), 215-220. (2020).

Kecheng Lei, Xiaoxia Gu, Alvaro G. Alvarado, Yuhong Du, Shilin Luo, Eun Hee Ahn, Seong Su Kang, Bing Ji, Xia Liu, Hui Mao, Haian Fu, Harley I. Kornblum, Lingjing Jin, Hua Li, Keqiang Ye Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. Journal of Hematology & Oncology, 13(1), 141. (2020).

Zhen Lei, Nan Wang, Hongwei Tan, Jimin Zheng, Zongchao Jia. Conformational Plasticity of the Active Site Entrance in E. coli Aspartate Transcarbamoylase and Its Implication in Feedback Regulation. International Journal of Molecular Sciences, 21(1). (2020).

Fu-Long Li, Yan-Yan Qiu, Yu-Cong Zheng, Fei-Fei Chen, Xu–Dong Kong, Jian-He Xu, Hui-Lei Yu Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds. Advanced Synthesis & Catalysis, 362(21), 4699-4706. (2020).