BL02U1

Min Su, Feng Gao, Qi Yuan, Yang Mao, De-lin Li, Youzhong Guo, Cheng Yang, Xiao-hui Wang, Renato Bruni, Brian Kloss, Hong Zhao, Yang Zeng, Fa-ben Zhang, Andrew R. Marks, Wayne A. Hendrickson, Yu-hang Chen Structural basis for conductance through TRIC cation channels. Nature Communications, 8(1), 15103. (2017).

Lifang Sun, Pu Chen, Yintao Su, Zhixiong Cai, Lingwei Ruan, Xun Xu, Yunkun Wu Crystal structure of thermostable alkylsulfatase SdsAP from Pseudomonas sp. S9. Bioscience reports, 37(3), BSR20170001. (2017).

Qi-Zheng Sun, Gui-Feng Lin, Lin-Li Li, Xi-Ting Jin, Lu-Yi Huang, Guo Zhang, Wei Yang, Kai Chen, Rong Xiang, Chong Chen, Yu-Quan Wei, Guang-Wen Lu, Sheng-Yong Yang Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers. Journal of Medicinal Chemistry, 60(14), 6337-6352. (2017).

Qingxiang Sun, Xin Yong, Xiaodong Sun, Fan Yang, Zhonghua Dai, Yanqiu Gong, Liming Zhou, Xia Zhang, Dawen Niu, Lunzhi Dai, Jia-Jia Liu, Da Jia Structural and functional insights into sorting nexin 5/6 interaction with bacterial effector IncE. Signal Transduction and Targeted Therapy, 2(1), 17030. (2017).

Xiangzhong Sun, Yaxin Li, Wenrong He, Chenggong Ji, Peixue Xia, Yichuan Wang, Shuo Du, Hongjiang Li, Natasha Raikhel, Junyu Xiao, Hongwei Guo Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase. Nature Communications, 8(1), 15758. (2017).

Zhongya Sun, Hao Zhang, Zhifeng Chen, Yiqian Xie, Hao Jiang, Limin Chen, Hong Ding, Yuanyuan Zhang, Hualiang Jiang, Mingyue Zheng, Cheng Luo Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays. Bioorganic & Medicinal Chemistry Letters, 27(9), 2003-2009. (2017).

Kong-Hung Sze, Wai-Hei Lam, Hongmin Zhang, Yi-hong Ke, Man-Kit Tse, Patrick C. Y. Woo, Susanna K. P. Lau, Candy C. Y. Lau, Jian-piao Cai, Edward T. K. Tung, Raymond K. C. Lo, Simin Xu, Richard Y. T. Kao, Quan Hao, Kwok-Yung Yuen Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response. Cell Chemical Biology, 24(2), 182-194. (2017).

Shuguang Tan, Hao Zhang, Yan Chai, Hao Song, Zhou Tong, Qihui Wang, Jianxun Qi, Gary Wong, Xiaodong Zhu, William J. Liu, Shan Gao, Zhongfu Wang, Yi Shi, Fuquan Yang, George F. Gao, Jinghua Yan An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nature Communications, 8(1), 14369. (2017).