BL02U1

Mark Zak, Po-wai Yuen, Xiongcai Liu, Snahel Patel, Deepak Sampath, Jason Oeh, Bianca M. Liederer, Weiru Wang, Thomas O’Brien, Yang Xiao, Nicholas Skelton, Rongbao Hua, Jasleen Sodhi, Yunli Wang, Lei Zhang, Guiling Zhao, Xiaozhang Zheng, Yen-Ching Ho, Kenneth W. Bair, Peter S. Dragovich Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. Journal of Medicinal Chemistry, 59(18), 8345-8368. (2016).

Menglong Zeng, Yuan Shang, Yoichi Araki, Tingfeng Guo, Richard L. Huganir, Mingjie Zhang Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Cell, 166(5), 1163-1175.e1112. (2016).

Menglong Zeng, Yuan Shang, Tingfeng Guo, Qinghai He, Wing-Ho Yung, Kai Liu, Mingjie Zhang A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function. Proceedings of the National Academy of Sciences, 113(22), E3081-E3090. (2016).

Liting Zhai, Lingling Feng, Lin Xia, Huiyong Yin, Song Xiang Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations. Nature Communications, 7(1), 11229. (2016).

Zhengsheng Zhan, Xia Peng, Qiufeng Liu, Fang Chen, Yinchun Ji, Shanyan Yao, Yong Xi, Yipeng Lin, Tiantian Chen, Yechun Xu, Jing Ai, Meiyu Geng, Wenhu Duan Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor. European Journal of Medicinal Chemistry, 116, 239-251. (2016).

Cheng Zhang, Qi Sun, Rongchang Chen, Xining Chen, Jinzhong Lin, Keqiong Ye Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits. Nucleic Acids Research, 44(15), 7475-7486. (2016).

Chunmao Zhang, Huaijie Hao, You Yu, Decong Kong, Shaolong Chen, Hua Jiang, Yuan Yuan, Yuling Zheng, Maojun Yang, Yongqiang Jiang Structural basis of the interaction between the meningitis pathogen Streptococcus suis adhesin Fhb and its human receptor. FEBS Letters, 590(9), 1384-1392. (2016).

Fan Zhang, Yang Song, Mohammad Ebrahimi, Liwen Niu, Maikun Teng, Xu Li Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae. Biochemical and Biophysical Research Communications, 477(4), 786-793. (2016).