BL02U1

Yao Zhang, Philbert Lee, Shichu Liang, Zuping Zhou, Xiaoyang Wu, Feng Yang, Hong Liang Structural Basis of Non-Steroidal Anti-Inflammatory Drug Diclofenac Binding to Human Serum Albumin. Chemical Biology & Drug Design, 86(5), 1178-1184. (2015).

Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug Stabilizing a Flexible Interdomain Hinge Region Harboring the SMB Binding Site Drives uPAR into Its Closed Conformation. Journal of Molecular Biology, 427(6, Part B), 1389-1403. (2015).

Lele Zhao, Yingqing Wang, Danyan Cao, Tiantian Chen, Qi Wang, Yanlian Li, Yechun Xu, Naixia Zhang, Xin Wang, Danqi Chen, Lin Chen, Yue-Lei Chen, Guangxin Xia, Zhe Shi, Yu-Chih Liu, Yijyun Lin, Zehong Miao, Jingkang Shen, Bing Xiong Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization. Journal of Medicinal Chemistry, 58(3), 1281-1297. (2015).

Li-Hua Zhao, X. Edward Zhou, Wei Yi, Zhongshan Wu, Yue Liu, Yanyong Kang, Li Hou, Parker W. de Waal, Suling Li, Yi Jiang, Adrian Scaffidi, Gavin R. Flematti, Steven M. Smith, Vinh Q. Lam, Patrick R. Griffin, Yonghong Wang, Jiayang Li, Karsten Melcher, H. Eric Xu Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3. Cell Research, 25(11), 1219-1236. (2015).

Qin Zhao, Chengcheng Wang, Chengyuan Wang, Hui Guo, Zhihao Bao, Minhua Zhang, Peng Zhang Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters. Nature Communications, 6(1), 7661. (2015).

Ye Zhao, Meihua Lu, Hui Zhang, Jing Hu, Congli Zhou, Qiang Xu, Amir Miraj Ul Hussain Shah, Hong Xu, Liangyan Wang, Yuejin Hua Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J. Nucleic Acids Research, 43(11), 5550-5559. (2015).

Qianqian Zheng, Yunlong Song, Wei Zhang, Neil Shaw, Weihong Zhou, Zihe Rao Structural views of quinone oxidoreductase from Mycobacterium tuberculosis reveal large conformational changes induced by the co-factor. The FEBS Journal, 282(14), 2697-2707. (2015).

Weili Zheng, Lin Qiu, Rui Wang, Xuhui Feng, Yaping Han, Yanlin Zhu, Dezhou Chen, Yijie Liu, Lihua Jin, Yong Li Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. Scientific Reports, 5(1), 12222. (2015).