BL02U1

Zengqin Deng, Kathleen C. Lehmann, Xiaorong Li, Chong Feng, Guoqiang Wang, Qi Zhang, Xiaoxuan Qi, Lin Yu, Xingliang Zhang, Wenhai Feng, Wei Wu, Peng Gong, Ye Tao, Clara C. Posthuma, Eric J. Snijder, Alexander E. Gorbalenya, Zhongzhou Chen Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase. Nucleic Acids Research, 42(5), 3464-3477. (2014).

Yue Ding, Xing Liu, Feifei Chen, Hongxia Di, Bin Xu, Lu Zhou, Xin Deng, Min Wu, Cai-Guang Yang, Lefu Lan Metabolic sensor governing bacterial virulence in Staphylococcus aureus. Proceedings of the National Academy of Sciences, 111(46), E4981-E4990. (2014).

Peter S. Dragovich, Guiling Zhao, Timm Baumeister, Brandon Bravo, Anthony M. Giannetti, Yen-Ching Ho, Rongbao Hua, Guangkun Li, Xiaorong Liang, Xiaolei Ma, Thomas O’Brien, Angela Oh, Nicholas J. Skelton, Chengcheng Wang, Weiru Wang, Yunli Wang, Yang Xiao, Po-wai Yuen, Mark Zak, Qiang Zhao, Xiaozhang Zheng Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic & Medicinal Chemistry Letters, 24(3), 954-962. (2014).

Xiaojie Duan, Songqing Hu, Peng Zhou, Yong Zhou, Yu Liu, Zhengqiang Jiang Characterization and crystal structure of a first fungal glyoxylate reductase from Paecilomyes thermophila. Enzyme and Microbial Technology, 60, 72-79. (2014).

Junping Fan, Daohua Jiang, Yan Zhao, Jianfeng Liu, Xuejun Cai Zhang Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B. Proceedings of the National Academy of Sciences, 111(21), 7636-7640. (2014).

Svetlana A Fayngerts, Jianping Wu, Camilla L Oxley, Xianglan Liu, Anastassios Vourekas, Terry Cathopoulis, Zhaojun Wang, Jian Cui, Suxia Liu, Honghong Sun, Mark A Lemmon, Lining Zhang, Yigong Shi, Youhai H Chen TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer. Cancer Cell, 26(4), 465-478. (2014).

Chong Feng, Yang Liu, Guoqiang Wang, Zengqin Deng, Qi Zhang, Wei Wu, Yufeng Tong, Changmei Cheng, Zhongzhou Chen Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition*. Journal of Biological Chemistry, 289(17), 11571-11583. (2014).

Han Feng, Jingjin Ding, Deyu Zhu, Xuehui Liu, Xueyong Xu, Ying Zhang, Shanshan Zang, Da-Cheng Wang, Wei Liu Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins. Journal of the American Chemical Society, 136(42), 14694-14697. (2014).