BL02U1

Zhiyi Wei, Suilan Zheng, Samantha A Spangler, Cong Yu, Casper C Hoogenraad, Mingjie Zhang Liprin-Mediated Large Signaling Complex Organization Revealed by the Liprin-α/CASK and Liprin-α/Liprin-β Complex Structures. Molecular Cell, 43(4), 586-598. (2011).

Wai-Ting Wong, Kwok-Chu Chan, Pui-Kin So, Hong-Kin Yap, Wai-Hong Chung, Yun-Chung Leung, Kwok-Yin Wong, Yanxiang Zhao Increased Structural Flexibility at the Active Site of a Fluorophore-conjugated β-Lactamase Distinctively Impacts Its Binding toward Diverse Cephalosporin Antibiotics*. Journal of Biological Chemistry, 286(36), 31771-31780. (2011).

Fangming Wu, Yiwei Liu, Zhiqiang Zhu, Hongda Huang, Bo Ding, Jihui Wu, Yunyu Shi The 1.9Å crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones. Journal of Structural Biology, 174(1), 213-222. (2011).

Lin Wu, Lifeng Pan, Zhiyi Wei, Mingjie Zhang Structure of MyTH4-FERM Domains in Myosin VIIa Tail Bound to Cargo. Science, 331(6018), 757-760. (2011).

Shutong Xu, Jian Wu, Bingfa Sun, Chen Zhong, Jianping Ding Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding. Nucleic Acids Research, 39(10), 4438-4449. (2011).

Shutong Xu, Chen Zhong, Tianlong Zhang, Jianping Ding Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins. Journal of Molecular Cell Biology, 3(5), 293-300. (2011).

Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao, Li-xia Liu, Wen-qing Jiang, Jing Liu, Jin-ye Zhang, Bin Wang, Stephen Frye, Yi Zhang, Yan-hui Xu, Qun-ying Lei, Kun-Liang Guan, Shi-min Zhao, Yue Xiong Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases. Cancer Cell, 19(1), 17-30. (2011).

Zhijian Xu, Zheng Liu, Tong Chen, TianTian Chen, Zhen Wang, Guanghui Tian, Jing Shi, Xuelan Wang, Yunxiang Lu, Xiuhua Yan, Guan Wang, Hualiang Jiang, Kaixian Chen, Shudong Wang, Yechun Xu, Jingshan Shen, Weiliang Zhu Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. Journal of Medicinal Chemistry, 54(15), 5607-5611. (2011).